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MEMBER PROFILES

DNA Genotek Inc.

Company Overview

All genetic research, analysis and testing starts with the collection of DNA samples. DNA Genotek is focused on developing products to enable easy and reliable collection, preparation and stabilization of high quality and high quantity nucleic acid (DNA and RNA) samples.

Since the company was incorporated in 1998 in Ottawa, Canada, it has invested in both product and market development activities resulting in widespread adoption of its offerings across multiple industries including genomic research, personalized medicine, and the molecular analysis and diagnostic arenas. The company launched their flagship Oragene-DNA Self-Collection Kit in 2004 and has successfully established itself as a leading provider of sample collection devices within the molecular epidemiology market. The company continues to extend its customer base to new markets and has expanded its product line to include products for RNA collection, for DNA collection from animals and for DNA collection from livestock. DNA Genotek supports more than 4000 customers in over 100 countries worldwide.

DNA Genotek's success is based on strong relationships with valued customers and partners, an innovative environment, and a passion for quality. While listening closely to their customers and keeping in tune with the market, DNA Genotek continues to add value to encompass full sample management solutions from sample collection, through processing, analysis and banking. Providing end-to-end solutions has enabled DNA Genotek to quickly acquire new customers while maintaining a strong base of repeat customers.

Awards

  • One of the World Economic Forum's 2006 Technology Pioneers
  • Medical Design Excellence Award "for In-vitro Diagnostics" 2010

Product Overview

DNA Genotek creates products that offer an all-in-one system for the collection, stabilization, transportation and purification of nucleic acids. Our current product line includes:

Oragene-DNA

The Oragene-DNA sample collection kit provides an all-in-one system for the collection, stabilization, transportation and purification of DNA from saliva. Oragene-DNA offers:

  • Easy collection, transportation and processing
  • Painless, non-invasive collection of high-quality, high quantity DNA
  • DNA is stable for years at ambient temperature and ideal for collection in extreme climates
  • Proven to perform as well as blood on downstream applications

Oragene-RNA

The Oragene-RNA for Expression Analysis Self-Collection Kit is the only all-in-one system for the collection, stabilization and transportation of high quality mRNA from saliva.

Oragene-ANIMAL

Oragene-ANIMAL is an all-in-one system for the collection, stabilization and preparation of DNA from saliva from mid-sized companion and lab animals.

Performagene-LIVESTOCK

Performagene-LIVESTOCK is an all-in-one system for the collection, stabilization and preparation of DNA from livestock nasal samples.

Technology that enables discovery and growth

Core to the value DNA Genotek products provide is the ability for our customers to scale their operations while minimizing associated costs and complexity. Examples include:

  • Collect more samples from patients or donors:
    • Convenient, at home or remote collection
    • Unlike blood, send the samples through the regular mail
    • Reliable and easy-to-use self-collection of samples
    • More samples without more phlebotomists
  • Event-based collection:
    • Quickly augment the size of a biorepository
  • Room temperature storage:
    • Collect and process more samples without investing money or lab footprint for cold storage
  • Full compatibility with automated processing
  • Bar-coded for sample traceability
  • Long-term stability at ambient temperature
    • Go back to the same sample for multiple tests
    • Store sample for redundancy testing
  • Customization:
    • Integrate sample from collection to analysis with defined logistical requirements
  • Flexible:
    • Fully proven and compatible with a range of processing equipment and analysis technologies

Tuberculosis Profile

Product Applications in Tuberculosis Research

DNA Genotek is proud to enable a variety of research projects that are focused on tuberculosis. Oragene-DNA samples remain stable at ambient temperatures making it ideal for collecting DNA from saliva in countries with high TB prevalence and in remote locations. Developing new diagnostic tools, vaccines and treatments are critical to stopping the TB epidemic. By participating in these important studies, DNA Genotek is making a significant contribution to the research that is essential to developing an effective treatment or cure for TB.

One such research project is the world's leading TB vaccine research site, the South African Tuberculosis Vaccine Initiative (SATVI) at the University of Cape Town. SATVI uses Oragene-DNA for a study aimed at identifying host correlates of protection against TB, following BCG vaccination. This study is looking at the genetic differences between infants who are either protected or not protected against TB, following BCG vaccination. The researchers are interested in determining if there is a genetic predisposition to susceptibility of TB by recruiting parents of both protected and unprotected infants. Over the course of the 4 year study, approximately 6,000 DNA samples will be collected with the Oragene-DNA Self-Collection Kits.

Another example is DNA Genotek's support of the International Centre for Diarrhoeal Disease Research in Bangladesh (ICDDR,B). The ICDDR,B has undertaken a study to determine the genetic variants associated with susceptibility to malnutrition and active tuberculosis among an ethnically and racially homogenous population. The study is using Oragene-DNA kits to collect DNA from approximately 2000 children to conduct a genome wide association study.

CSR Profile

The DNA Genotek Helping Hands program is designed to assist organizations that are innovators in disease research, disease prevention and treatment. Within this program, DNA Genotek applies its technology and expertise to break down barriers that impede DNA sample collection or treatment and prevention of disease. The experience we have garnered enables us to support programs that have a long-term impact on significant numbers of people and cover a diverse range of health issues. The goal of the program is to help accelerate research and advance the fight against disease across the globe. This program has allowed DNA Genotek to support a variety of important projects.

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