TB is the leading cause of death among people with HIV/AIDS, responsible for 23%, or one in four, of all AIDS-related deaths. In 2007 alone, TB killed over 450,000 HIV-positive individuals. Currently, one-third of people living with HIV/AIDS are also living with latent TB. These individuals are 20-40 times more likely to progress to active TB disease than those not infected with HIV. Progress in the fight against HIV will be hampered until the global community steps up action on TB.